SeqSize
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General Information
- Application's name: Sequencing Size and Power
- Application's acronym: SeqSize
- Scientific domain: domain
- Contact person: Dean Palejev, palejev<>math.bas.bg
- Main Developers: Dean Palejev, Bulgarian Academy of Sciences, Institute of Mathematics and Informatics
- Co-developers: -
- Allocation period: '
- Web site:
Objectives of the computing project
Estimating the Statistical power and required sample size analysis for RNA and DNA sequencing experiments, including differential expression and structural variants.
Application's description
The application estimates, using MPI, the statistical power and required sample size analysis for RNA and DNA sequencing experiments, including differential expression and structural variants. Finding the required sample size is required for determining the optimal sample size when designing sequencing studies and for grant budgeting.
Results expected in the allocation period
Designing a base framework for finding the required sample size of RNA-seq experiments that use negative binomial models (e.g. DESeq, edgeR and Cuffdiff 2).